PORPHYRIN PHOTOSENSITIZATION AND PHOTOTHERAPY
نویسندگان
چکیده
منابع مشابه
Morphological families of self-assembled porphyrin structures and their photosensitization of hydrogen generation.
Varying the solution growth conditions of cooperative binary ionic solids composed of anionic and cationic metalloporphyrins produces a series of families of self-assembled structures that efficiently and durably photosensitize the evolution of hydrogen.
متن کاملSelf-assembled porphyrin nanodiscs with structure-dependent activation for phototherapy and photodiagnostic applications.
The abilities to deliver and subsequently activate a therapeutic at the intended site of action are two important challenges in the synthesis of novel nanoparticles. Poor tumor permeability as a result of a dense microenvironment can impede the delivery of nanoparticles to the site of action. The design of a sub-40 nm activatable porphyrin nanodisc, based on protein-induced lipid constriction, ...
متن کاملTopical photodynamic therapy using different porphyrin precursors leads to differences in vascular photosensitization and vascular damage in normal mouse skin.
Different distributions of hexyl aminolevulinate (HAL), aminolevulinic acid (ALA) and methyl aminolevulinate (MAL) in the superficial vasculature are not well studied but they are hypothesized to play an important role in topical photodynamic therapy (PDT). The colocalization of fluorescent CD31 and protoporphyrin IX (PpIX) was calculated using confocal microscopy of mouse skin sections to inve...
متن کاملPhotosensitization by drugs*
Certain drugs are known to elicit photosensitivity side effects. A satisfactory understanding of the involved mechanistic aspects is necessary to anticipate the photosensitizing potential. We have used tiaprofenic acid (TPA), a photosensitizing nonsteroidal antiinflammatory drug, to illustrate the methodology followed to address this problem. After studying the photophysical and photochemical p...
متن کاملSelective oxidative degradation of organic pollutants by singlet oxygen-mediated photosensitization: tin porphyrin versus C60 aminofullerene systems.
This study evaluates the potential application of tin porphyrin- and C(60) aminofullerene-derivatized silica (SnP/silica and aminoC(60)/silica) as (1)O(2) generating systems for photochemical degradation of organic pollutants. Photosensitized (1)O(2) production with SnP/silica, which was faster than with aminoC(60)/silica, effectively oxidized a variety of pharmaceuticals. Significant degradati...
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ژورنال
عنوان ژورنال: Photochemistry and Photobiology
سال: 1986
ISSN: 0031-8655,1751-1097
DOI: 10.1111/j.1751-1097.1986.tb05647.x